Dindolyl Methane, or DIM as it is commonly referred to, is a very popular supplement for bodybuilders and others who are interested in increasing the growth of their muscles. However there have been recent reports of health risks that DIM can trigger. DIM can cause liver damage when taken in excessive amounts. Kidney damage can also be a risk, and could result in kidney failure. The long-term health risks associated with DIM cause many athletes and bodybuilders ask the question: should I take a supplement with DIM?
Most people use diindolylmethane as a supplement to increase the production of testosterone. Testosterone is believed to function as an anandrogen, meaning that it can cause hormonal changes in tissues. DIM has been shown in studies to mimic the effects of testosterone, and other hormones. Certain manufacturers have added diindolylmethane (DIM) to their products to boost their popularity in male circles, as men produce more testosterone than women do. The theory is that men respond to a product that replicates the effects of testosterone naturally produced.
This is why numerous companies promote DIM as a cancer suppressor. Although diindolylmethane is effective in reducing tumor growth in laboratory animals it was given orally to the animals. To achieve the same effect in humans, diindolylmethane would have to be consumed at high doses over a prolonged period of time. The animals that were studied did not show any indications of cancer for a number of years. However, they all developed liver disease after consuming excessive amounts of diindolylmethane. To have a closer look at the way DIM works in the body, you should contact a medical practitioner.
According to the US National Institute of Environmental Health Safety and Security, the only way to show that DIM is effective in treating breast cancer is to conduct an experiment in which cells from healthy breast cancer cells are exposed to high doses of diindolylmethane over a period of time. Like any chemical there are pros and cons associated with using it. Its advantages include the ability to mimic hormones. This lets you create insulin that can stop cancer cell growth. The disadvantages are that diindolylmethane produces a damaging chemical known as DMSO. Know more about dim (diindolylmethane) now.
One of the most commonly used claims about diindolylmethane’s usage as an treatment for various ailments is that it functions as an natural, antibacterial, anticancer, and anti-fungal agent. The National Institute of Health, in their exhaustive study of supporting data, concluded that there was no evidence to support these claims. According to the Institute of Chemical Technology, there was no research conducted to support this assertion. In a thorough review of the safety profile of the firestone, the Institute of Chemical Safety concluded that the evidence provided by pharmaceutical companies on the benefits for humans of diindolylmethane was not reliable.
In the May 2021 issue of the Journal of Toxicology and Environmental Health, van der Goes, et al. pointed out numerous potential hazards that could be posed by diindolylmethane’s use including allergic reactions to the skin, asthma attacks, dizziness, headaches, and respiratory issues. They also said that the recommended daily dose for this chemical is 0.2 milligrams, which is about one tenth of a teaspoon. It is not known what the concentration is when this chemical is mixed with other substances. Since this substance hasn’t been thoroughly examined, it isn’t considered safe at any point.
The abstract of the view suggests that the use of diindolylmethane (DIEM) in the context of treating cancer is based on the principle of inhibiting the intracellular inhibition of pyruvate’s pyruvate metabolite via flavenoids, and thus preventing accumulation of oxalates in renal tubule cells and Adenine granulocytes. Metabiplicate toxicology studies on the drug have not shown that this chemical can cause overdose. The Food and Drug Administration approved this substance as a prescribed drug in June 1996. According to the FDA the company that makes firestone tincture is currently in the process of conducting two major studies – one in Europe and one in the United States.
The view abstract also shows the use of diindolylmethane in cancer treatment is based on the principle of inhibiting intracellular inhibition by flavenoids that regulate pyruvate metabolism and thus stopping the accumulation of oxalates and adenine in renal tubule cells. However, the drug metabiplicate toxicity studies did not provide evidence convincing that consumption of this chemical causes an overdose. In June 1996, the Food and Drug Administration approved this drug as a prescription drug. According to the FDA the company that makes firestone Tincture is currently conducting two major trials in Europe and the United States. According to FDA, the FDA states that the maker of firestone Tincture is currently conducting two major trials in Europe as well as one in the United States.